The Chemical and Engineering News (C&EN), a publication of the American Chemical Society is a leading source of technical information for the Life Sciences industry. An article published in early July 2016 provides a summary of the world leading pharmaceutical companies now developing deuterated drugs. Successful deuterated drugs have up to three ways they can enhance the efficacy of similar non-deuterated drugs. First deuterium reduces the rate at which the body can metabolize the medicine. Secondly due to deuterium’s stability enhancement, longer therapeutic life time may result. Thirdly, the longer the lifetime, the higher the potential to reduce the initial dosage level. Lower doses may lead to reduced side effects. Isowater® is supporting the use of deuterium in the pharmaceutical industry through developing strong supply chain products such as multiyear supply arrangements.
http://cen.acs.org/articles/94/i27/Deuterium-switcheroo-breathes-life-old.html