The Canadian nuclear industry has long been a world leader in research and technology development, from manufacturing novel reactors to globally exporting items such as radioisotopes and deuterium oxide. This progress in technology is causing industries around the world in all sectors to be disrupted, including those related to the use of deuterium oxide. “We’re … Continue reading Isowater Corporation: “Connecting Nuclear Products to Non-Nuclear Markets” →

In the continuing clinical trials, Avanir Pharmaceuticals’ drug, AVP-786, is showing the progress being made in the use of deuterium in medical science. Successes like this pharmaceutical will continue to drive forward product development centered around the unique properties of deuterium by the world’s drug developers via their innovative R&D. Furthermore, advancements like this in … Continue reading AVP-786: Progress in the Use of Deuterium in Alzheimer’s Treatment →

The global pharmaceutical industry has been advanced significantly by Vertex [NASDAQ: VRTX] and their potential improvement for the treatment of cystic fibrosis via the use of a novel deuterated drug CTP-656. Vertex’s stock increased a record amount, boosting their market cap by 8 billion USD with shares up 24% after the company shared their data from clinical studies of … Continue reading Deuterated Drug Purchase Agreement Continues to Validate Deuterium’s Growing Role in the Future of Medicine →

Isowater is pleased to see this precedent setting FDA approval in place for Austedo  by Teva. It has had the developmental name of SD-809. As it is for the treatment of chorea, which is associated with Huntington’s disease, it offers an improved product to reduce the random involuntary twisting movements that accompany people with Huntington’s.  … Continue reading First Deuterated Drug, Austedo (deutrabenazine) by Teva approved by FDA, April 04, 2017 →

Deuterium oxide is being used in key pharmaceutical applications as reported by Dr. Sarah Harding of Specialty Chemicals Magazine in their Pharmaceuticals section of the April 2017 magazine. With a focus on the variety of Life Sciences applications for deuterium oxide that are used to help patients, Isowater plays a key role. Deuteration offers a … Continue reading Deuterium use in Life Science Applications Highlighted in Specialty Chemicals Magazine →

 The Chemical and Engineering News (C&EN), a publication of the American Chemical Society is a leading source of technical information for the Life Sciences industry. An article published in early July 2016 provides a summary of the world leading pharmaceutical companies now developing deuterated drugs.   Successful deuterated drugs have up to three ways they can … Continue reading The Chemical and Engineering News (C&EN) reports on Deuterated Drugs & Isowater’s Role →

The excitement and growth potential of deuterated pharmaceuticals is going main-stream as reported in the Economist magazine in their Medical Chemistry section (see link below). With the emphasis being “Drugs that live long will prosper”, the article nicely summarizes the outlook for deuterated pharmaceuticals. The ending sentence “…a basic fact: deuterated drugs will soon be … Continue reading The Economist Magazine Reports on Deuterated Pharmaceuticals →

First Auspex Pharmaceuticals announces its IPO priced at $12.00 per share, and now Concert Pharmaceuticals announces its IPO at $14.00 per share.  Auspex and Concert are both working on developing drugs containing deuterium (H2) in place of protium (H1) at key positions.  Both companies have pharma products in the pipeline and both have products that … Continue reading Another Major Investment in Deuterium Technology for Pharmaceuticals →

Auspex Pharmaceuticals Inc has raised $35 million which will advance the clinical trials of its deuterium substituted drug SD-809 designed for the treatment of chorea associated with Huntington’s disease.  In addition, the company has appointed an industry veteran, Gerald Proehl, to its Board of Directors says the article in Digital Journal. Auspex has a pipeline … Continue reading Major Investment in Technology for Pharmaceuticals →

The growing use of deuterium in the high tech sector has again been demonstrated. In a news release by PR Newswire, Toshiba has announced a major breakthrough in the fabrication of low-power semiconductors.  The new technology reduces the stress induced leakage current – the enemy of power efficiency – by at least 30%.  The process … Continue reading Toshiba Makes a Large Advance in Semi-Conductor Fabrication Using Deuterium →

This article is one of an ‘Expert Tips’ series from Waters, and it has useful recommendations for deuterium labelling of peptides for protein structural dynamics and conformational changes.  Deuterium oxide is used to label proteins for specific times and analysis performed by mass spectroscopy with appropriate software.  This is an example of the applications of … Continue reading Labeling for Mass Spec analysis →

India has perhaps the world’s most advanced nuclear energy program.  The nation has some 20 reactors now (90% of which are heavy water moderated types) and plans to add approximately 60,000 MW of new nuclear energy generation by 2032.  Heavy water reactors will remain a significant portion of the planned role out.  In addition to … Continue reading Will India need to import heavy water? →

Here is an interesting link about Samsung’s activities to make a better microchip through use of deuterium (heavy hydrogen).  The core technology was discovered at the University of Illinois University in the late 1990s and since 2010 it has been progressing towards commercialization.  Deuterium has superior properties to regular hydrogen and allow chips to run … Continue reading The benefits of deuterium in building a better microchip →

One of the many examples of innovation based on deuterium’s role in non-radioactive life science applications is with living cells.  A technique uses the fact a carbon-deuterium bond vibrates at a unique frequency different from the normal carbon-hydrogen bond to support research into protein development inside the brain as long-term memory is formed. http://phys.org/news/2013-10-chemist-optical-imaging-technique-mystery.html To … Continue reading Life science applications with living cells →